Tuesday, March 13, 2012

Refresh Roundup: week of March 5th, 2012

Refresh Roundup: week of March 5th, 2012
Your smartphone and / or tablet is just begging for an update. From time to time, these mobile devices are blessed with maintenance refreshes, bug fixes, custom ROMs and anything in between, and so many of them are floating around that it's easy for a sizable chunk to get lost in the mix. To make sure they don't escape without notice, we've gathered every possible update, hack, and other miscellaneous tomfoolery we could find during the last week and crammed them into one convenient roundup. If you find something available for your device, please give us a shout at tips at engadget dawt com and let us know. Enjoy!

Continue reading Refresh Roundup: week of March 5th, 2012

Refresh Roundup: week of March 5th, 2012 originally appeared on Engadget on Sun, 11 Mar 2012 15:32:00 EDT. Please see our terms for use of feeds.

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Friday, March 9, 2012

Polley, Delpy bring films to Tribeca Film Festival

FILE - In this Sept. 11, 2011 file photo, director-screenwriter-actress Sarah Polley poses for a portrait to promote her film, "Take this Waltz," during the 36th Toronto International Film Festival in Toronto, Canada. Polley's ?Take This Waltz? starring Michelle Williams and Seth Rogen as a married couple stressed by the temptation of an affair, will be shown at the Tribeca Film Festival. (AP Photo/Carlo Allegri, file)

FILE - In this Sept. 11, 2011 file photo, director-screenwriter-actress Sarah Polley poses for a portrait to promote her film, "Take this Waltz," during the 36th Toronto International Film Festival in Toronto, Canada. Polley's ?Take This Waltz? starring Michelle Williams and Seth Rogen as a married couple stressed by the temptation of an affair, will be shown at the Tribeca Film Festival. (AP Photo/Carlo Allegri, file)

FILE - In this Jan. 23, 2012 file photo, Julie Delpy, a cast member, co-writer and director of "2 Days in New York," poses with cast member Chris Rock at the premiere of the film at the Sundance Film Festival in Park City, Utah. Delpy's ?2 Days in New York," a follow-up to her ?2 Days in Paris," starring Delpy and Chris Rock, will be shown at the Tribeca Film Festival. (AP Photo/Chris Pizzello, file)

FILE - In this Oct. 22, 2011 file photo, British director Michael Winterbottom arrives for the BFI London Film Festival screening of "Trishna" premiere at a central London Cinema. Winterbottom's "Trishna," an adaption of Thomas Hardy's "Tess of the d'Urbervilles" starring Freida Pinto, will be shown at the Tribeca Film Festival. (AP Photo/Jonathan Short, file)

(AP) ? Sarah Polley, Julie Delpy and Michael Winterbottom will bring films to this year's Tribeca Film Festival.

The festival announced the second half of its slate Thursday. After earlier announcing its films in competition, this batch collects the films that will play in Tribeca's Spotlight and Cinemania sections, as well as its ESPN-sponsored sports festival.

Delpy's "2 Days in New York" is a follow-up to her "2 Days in Paris." In the comedy, Delpy stars with Chris Rock as a New York couple with visiting family from Paris.

Polley's "Take This Waltz" is the Canadian actress' follow-up to her debut, "Away From Her." It stars Michelle Williams and Seth Rogen as a married couple stressed by the temptation of an affair.

Winterbottom's "Trishna" is an adaptation of Thomas Hardy's "Tess of the d'Urbervilles." It stars Freida Pinto. Winterbottom, the director of "The Trip" and "24 Hour Party People," previously adapted Laurence Sterne's "Tristram Shandy" in a deconstructed comedy.

The directors of the Oscar-nominated "Persepolis," Marjane Satrapi and Vincent Paronnaud, will present their "Chicken With Plums," a French-language film starring Mathieu Amalric as a violin player in 1950s Tehran.

Starring in other Tribeca selections are: Maggie Gyllenhaal ("Hysteria"), Greta Gerwig ("Lola Versus"), John Hawkes ("The Playroom"), Salma Hayek ("As Luck Would Have It") and Jesse Eisenberg ("Free Samples").

Documentaries will tackle a variety of subjects, including baseball's knuckleball ("Knuckleball!"), creativity in the time of President Ronald Reagan ("Let Fury Have the Hour"), the rock band Queen ("Queen: Days of Our Lives") and male beauty ("Mansome," by Morgan Spurlock).

The 11th annual Tribeca Film Festival will be held April 18-29. Opening the festival will be "The Five-Year Engagement," a comedy starring Jason Segel and produced by Judd Apatow.

___

Online:

http://www.tribecafilm.com/festival/

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2012-03-08-Tribeca%20Film%20Festival/id-1d1c93c93a734730aa3020663d67d504

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Thursday, March 8, 2012

Cells may spare kidney transplant rejection drugs

WASHINGTON (AP) ? An experimental technique seems to be freeing some kidney transplant patients from having to take anti-rejection drugs.

Researchers transplanted certain cells from the kidney donor's bone marrow along with the new organ. Five of eight transplant recipients who tried the method so far were off immune-suppressing medication up to 2? years later, the researchers reported Wednesday.

The preliminary results were considered important enough to be published in the journal Science Translational Medicine even though the study still is under way, because the technique worked for patients who didn't have well-matched or related donors.

The idea is that if a sort of twin immune system takes root and lasts, it can allow the patient's body to accept the foreign organ and not attack it, said study co-author Dr. Suzanne Ildstad of the University of Lousville. Scientists call it chimerism.

"The most reliable indicator of really being successful at taking someone off immune-suppressing drugs is durable chimerism," says Ildstad, who teamed with doctors at Chicago's Northwestern Memorial Hospital for the research.

Transplant recipients usually must take multiple immune-suppressing pills for life to prevent rejection of their new organ. Those drugs cause lots of side effects, such as raising the risk of cancer and kidney damage.

Other scientists are attempting to tap bone marrow to induce immune tolerance, with varying success.

Ildstad's approach transfuses a special mix of bone marrow cells including blood-producing stem cells and another type named "facilitating cells" that are thought vital for a successful transplant. She filters out still other cells that can become too aggressive and cause a life-threatening disorder named graft-versus-host disease.

Transplant recipients had radiation and chemotherapy, not destroying their own bone marrow but tamping it down to make space for the donated cells, explained study co-author Dr. Joseph Leventhal, a Northwestern transplant surgeon. Five patients who had the dual immunity a year later were weaned off all drugs. Two others whose hybrid immunity faded are faring well using a low dose of one anti-rejection drug. One patient needed a repeat transplant after an infection and didn't get to try weaning.

Much more study is needed to find the best approach but "the results are striking," Dr. Tatsuo Kawai of Massachusetts General Hospital wrote in an accompanying editorial. He is part of a team that in 2008 reported the only other success with a small number of mismatched transplants.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/b2f0ca3a594644ee9e50a8ec4ce2d6de/Article_2012-03-07-Transplant-Immunity/id-78ffc3baab8e43b6bda089d6241b357f

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Wednesday, March 7, 2012

Poet's Musings: The Literary Agents Speak to the Novelists

* Although the writing is good, the characters strong, and the story compelling, I just didn't fall in love with the book.? Also, I'm dating another book right now.

* Given the market for fiction right now, I don't feel I can successfully represent this book.? Your book's like a little piggy that's not going to market!

* I found your characters to be one-dimensional like the paper they were written on.? I simply wasn't drawn into the story in a two-dimensional way. I used to study art. My favorite color is red. I went to Vassar. I live in Brooklyn.

* Thank you for the opportunity to read your novel. I don't feel I'm the best agent to represent it. I wish you much success. Being a writer, you must find some perverse appeal to this robotic kind of rejection.

* Thank you for your query.? Due to the overwhelming number of queries we receive, we are overwhelmed. Unfortunately, we represent a small number of established clients, as opposed to an established number of small clients. Wait--I mean "fortunately."? Therefore we must pass on the opportunity to represent you.? We are passing.

* I used to like reading novels. Now I hate it. I have lunch with famous writers. I hate that, too. My favorite novel was published in 1951. I still masturbate to it. Editors are insufferable.? New York is expensive, loud, crowded, and dirty. Help!

* You think Ingvold is an interesting character.? We don't. In fact, we had a good laugh when I read the sentences describing him out loud.? How can you stand to live on the West Coast? Isn't that almost China? Who names characters "Ingvold"? Ew.

* I'm afraid I lost interest in the book halfway through. I also lost the pages from the second half. Sorry.? Good luck!? I start drinking gin at noon every day.

* Your novel contains references to several different kinds of blades. I couldn't possibly represent it because I have a terrible fear of castration.

* I wasn't offended at all by your premise, unusual though it is. I just don't want to represent the book. I love being so picky! Ha, ha, ha!

* I've never heard of you. No one I know has heard of you. Where did you get your MFA?? Did you get an MFA? Who do you know? The novel may be good, but I don't have time to read it, and no one's ever heard of you. Are you in Witness Protection?? We represent celebrity novelists with multi-platform appeal that we can leverage. Am I getting through to you?

Source: http://poetsmusings-muser.blogspot.com/2012/03/literary-agents-speak-to-novelists.html

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Tuesday, March 6, 2012

NFL bounties amount to incentive system run amok (AP)

[unable to retrieve full-text content]AP - To Hall of Fame defensive back Ronnie Lott, the thousands of dollars New Orleans Saints players were paid under their bounty system from 2009-11 is not all that different from the helmet stickers handed out at lower levels of the game.

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20120306/ap_on_sp_fo_ne/fbn_bounties

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CVS Mix-Up Of Children's Fluoride Tablets With Cancer Drug Is Inexcusable (ContributorNetwork)

[unable to retrieve full-text content]ContributorNetwork - COMMENTARY | A CVS pharmacy in Chatham, New Jersey, accidentally switched chewable children's fluoride tablets with the breast cancer drug Tamoxifen. Tamoxifen is used to treat estrogen-positive breast cancer and it is not meant for children. The New Jersey State Attorney General's Office is looking into how this happened. A report by the New York Daily News states that CVS must respond to the Attorney General's inquiry by March 7.

Source: http://us.rd.yahoo.com/dailynews/rss/cancer/*http%3A//news.yahoo.com/s/ac/20120305/hl_ac/11048074_cvs_mixup_of_childrens_fluoride_tablets_with_cancer_drug_is_inexcusable

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Friday, March 2, 2012

Justin Bieber's Birthday Wish List

MTV News goes shopping in New York City to find the prince of pop the best gift, from a $20,000 watch to a Bentley.
By John Mitchell, with reporting by Christina Garibaldi


Justin Bieber arrives at the "Never Say Never" L.A. premiere
Photo: Kevin Winter/ Getty Images

<P><a href="/news/articles/1680195/justin-bieber-18th-birthday-top-moment.jhtml">Justin Bieber's 18th birthday</a> is here and everyone, from <a href="/news/articles/744682/.jhtml">his mentor Usher</a> to <a href="/news/articles/744688/.jhtml">his biggest fans</a>, is super excited! But what do you get the boy who already has everything? MTV News' Christina Garibaldi hit the streets of NYC to find out, visiting some of the Big Apple's most exclusive big-name retailers to find the pop prince the perfect birthday gift. Anyone who's seen MTV's classic "Cribs" knows that the rich and famous love cars, and "the more the merrier" seems to be the motto when it comes to filling your garage with sweet rides. Biebs already has a Ferrari and a Cadillac Batmobile, so what more does he need? Paul at Manhattan Motorcars thinks he's got just the ticket: the redesigned 2012 Bentley Continental GTC. "Very sporty car, definitely aimed at a younger buyer," Paul told MTV News. "Completely hand-built, hand-crafted in England. Just a blast to drive." <CENTER><embed src="http://media.mtvnservices.com/mgid:uma:video:mtv.com:744681/cp~name%3Dnews%26id%3D1680192%26vid%3D744681%26uri%3Dmgid%3Auma%3Avideo%3Amtv.com%3A744681" width="430" height="242" type="application/x-shockwave-flash" allowFullScreen="true" allowScriptAccess="always" base="."></embed></CENTER> With a new ride lined up, Bieber's going to need a new pair of shades to keep the sun out of his precious peepers while he's cruising around Hollywood. For those, MTV visited Jordan Silver at Silver Lining Opticians. "Some of the most amazing pieces I think Justin might like are Persol, Ray Ban and some of the brands that did car collaborations in the '80s," Silver said. "One we just got in is by Maserati. It's a shield with three sets of lenses, interchangeable, and two sets of temples so that when you're traveling at high speeds you might need the extra protection of the cable temple." The cost? A cool $1,200. But that's pocket change to <a href="/news/articles/1678337/justin-bieber-lil-wayne-studio-visit.jhtml">Bieber's pals like Lil Wayne</a>, who hit the recording studio with the "Baby" singer last month. If Bieber's girl Selena Gomez is feeling sentimental about the dog they recently adopted, she could hit up Trax NYC for a $18,000 23-carat bulldog pendant. "Got some pink diamonds in the eyes. Yellow diamonds, black diamonds, all hand-set," Trax's Paul Mazza told MTV News. For an even pricier gift, Christina checked out some of Trax's blinged-out watches. "If you look at it right here, there's a lot of diamonds," Mazza said, showing off a $20,000 watch featuring 35 carats in diamonds. "This is something that definitively garners a lot of attention. ... Got one for every day of the week, different colors. It doesn't get any better than this." <I>What would you get Justin Bieber for his 18th birthday? Leave your comment below!</I> <b>Happy 18th birthday, <a href="http://www.mtv.com/music/artist/bieber_justin/artist.jhtml">Justin Bieber</a>! Now that we've counted down the superstar's 18 greatest moments, stick with MTV News as we celebrate the milestone all day.</b></p>

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Source: http://www.mtv.com/news/articles/1680248/justin-bieber-birthday-gifts.jhtml

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